The contrast of cold and warm is one of the writing bright spots of Treatise on Warm-Heat Diseases, which is to highlight the warm disease. The paper takes clause 1 of Treatise on Warm-Heat Diseases as an example, taking the analysis of the differences of basic concepts of cold damage and warm disease as the breakthrough point, according to the order of the contents of the clause, clarifying and emphasizing the profound meanings of four important concepts of warm disease included in this article. "warm evil" is the name of the total etiology of warm disease, distinguishing from cold evil of cold damage. "Upper receive" is the way that warm evil invades human body, while cold evil’s can be called under receive. Inverse transmission particularly refers to the disease transmission that from the meridian and viscera of hand taiyin lung to the hand jueyin pericardium in warm disease, which is compared with the disease transmission from the foot taiyang bladder to the foot yangming stomach in cold damage. Therefore, inverse transmission and sequential transmission are based on the transmission property comparison about cold damageand warm disease those two categories of exogenous febrile disease, they cannot be only interpreted limiting the scope of warm disease. "yingwei qixue "cannot be equated with"weiqi yingxue", the former mainly focuses on physical bases and physiological functions, while the latter represents the four stages, four major syndrome groups, four treatment principles and prescriptions for the occurrence and development of warm disease, which emphasizes the pathology. Therefore, the physical bases and physiological functions of the human body are same, but the pathogenesis transmission and treatment of warm disease and cold damage are different. The paper respects the original work, explores and analyzes it, restores the original meaning of the first clause of the classic Treatise on Warm-Heat Diseases, and corrects certain insider’s vague understanding.