To manage medicinal products by registration is a universal regulatory measure to ensure public health. Traditional Chinese medicine (TCM) is an important carrier of TCM theory and clinical practice. The registration management of TCM products has its own particularity. In 2017, the Law of the People"s Republic of China on TCM has put forward the development policy of TCM which should conform to the TCM characteristics. It not only marks a new development period for TCM industry, but also poses new challenges to the registration management of TCM in China. There is an urgent need to study and formulate the supporting documents or revise existing regulations to adapt to the spirit of the law. The European Union (EU) has got great achievement in the field of herbal medicinal regulation since the introduction of Directive 2004/24/EC. This paper made a systematic review of the legislative system of European herbal medicinal product. The main European regulatory characteristics and the enlightenments to administration of TCM products in China were deeply analyzed. The purpose is to provide reference for the reform of administration of TCM under background of the law of the People"s Republic of China on TCM.